Charlene (Lagasse) Darby, 73, of Manchester died Sunday November 21, 2021 at Manchester Memorial Hospital. Born in Madawaska, ME, she was the daughter of the late Donat and Catherine (Belanger) Lagasse and had lived in Manchester for many years. Charlene was a caring and selfless woman throughout her life, going so far as to refuse being placed on the heart transplant list so that a younger person might benefit. She is survived by her brothers Bert Lagasse of Manchester and Ronnie Lagasse and his wife Claudette; her goddaughter Ann Gagne and her husband Gary of Jacksonville, FL; her grandchildren Eric Gagne and his wife Ashley, and Casey Gagne; and her great-granddaughter Allison. Funeral service will be private and at the convenience of the family. For online condolences please visit www.tierneyfuneralhome.com.